Letter A

Apolipoprotein A-I

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APOA-I.

The major protein component of HDL (high density lipoprotein) and a relatively abundant plasma protein.

APOA-I is instrumental in promoting the transfer of cholesterol into the liver where it is metabolized and then excreted via the intestine from the body.

The gene locus for APOA-I is on chromosome 11q23. A number of genetic variants of APOA1 are known, including ApoA-I Milano

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