Letter B

BASE breast cancer gene

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A breast cancer gene first reported in 2003 that encodes a protein secreted only by breast cancer and salivary gland cells.

Hence the name, <B>BASE</B> (<B>B</B>reast cancer <B>A</B>nd <B>S</B>alivary gland <B>E</B>xpression).

The normal breast makes very little, if any, of the BASE protein whereas certain kinds of breast cancers produce quite a lot of it.

Determining the levels of BASE in the blood may be of use in screening for breast cancer and for following a patient's progress on breast cancer treatment

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