Letter C

Cutis laxa

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A dermatologic condition characterized by unusually loose skin which may hang in pendulous folds.

Cutis laxa is usually a genetic disorder.

A mild autosomal dominant form can be caused by mutation in the elastin gene (the ELN gene).

Mutations in the gene encoding fibulin-5 (FBLN5) can cause either autosomal dominant or a more severe autosomal recessive form of cutis laxa.

There is also an X-linked type of cutis laxa

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