Letter F

Focal gigantism

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<B>1.</B> The excessive growth of a specific body part such as a hand or foot, as with increased blood supply to that part.

<B>2.</B> The excessive growth of a combination of particular body parts, as is characteristic of a congenital malformation syndrome called the Wiedemann-Beckwith syndrome.

Focal gigantism may occur before or after the bones fuse.

If it occurs afterwards, it causes disfigurement, as in acromegaly.

Surgery for mass reduction may sometimes improve function.

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