Lamin A
Abbreviated LMNA.
A gene on chromosome 1 that encodes a protein which is a key component of the membrane surrounding the cell nucleus.</P> Mutations in the LMNA gene are responsible for a number of genetic disorders including: > >Progeria syndrome, >Emery-Dreifuss muscular dystrophy type 2, >Limb girdle muscular dystrophy type 1B, >Charcot-Marie-Tooth disorder type 2B1, >The Dunnigan type of familial partial lipodystrophy, >Mandibuloacral dysplasia and >A familial form of dilated cardiomyopathy.</LI></UL>