Letter M

Meiotic nondisjunction

1 views

Failure of two members of a chromosome pair to separate (disjoin) during meiosis so that both go to one daughter cell and none to the other.

This mechanism is responsible for the extra chromosome 21 in trisomy 21 (Down syndrome) and for extra and missing chromosomes causing other birth defects and many spontaneous abortions (miscarriages)

Share this definition

Medical disclaimer

The information on this page is for educational and informational purposes only and does not constitute medical advice in any way.

  • It does not replace the advice of a physician, pharmacist or other healthcare professional.
  • It does not represent a prescription of drugs, diagnostic exams or therapies.
  • In case of symptoms, doubts or concerns about your health, always consult a qualified physician.

In case of emergency call 911 (US) or 112 (EU).