Letter P

PANDAS

1 views

An acronym for <B>P</B>ediatric <B>A</B>utoimmune <B>D</B>isorders <B>A</B>ssociated with <B>S</B>trep.

PANDAS is the sudden onset of symptoms like those of obsessive-compulsive disorder or Tourette syndrome following infection with streptococcus bacteria, caused by an autoimmune reaction that affects the basal ganglia in the brain.

If tics are seen, they may or may not be choreaform like those of Sydenham chorea, a closely related condition that can follow a bout of rheumatic fever, which is caused by the streptococcus bacteria.

Diagnosis is primarily by observation, although a blood marker for the disorder has been identified.

Treatment is by plasmapheresis or intravenous immunoglobulin, prophylactic antibiotics, and/or medication for specific symptoms.

Share this definition

Medical disclaimer

The information on this page is for educational and informational purposes only and does not constitute medical advice in any way.

  • It does not replace the advice of a physician, pharmacist or other healthcare professional.
  • It does not represent a prescription of drugs, diagnostic exams or therapies.
  • In case of symptoms, doubts or concerns about your health, always consult a qualified physician.

In case of emergency call 911 (US) or 112 (EU).