Letter R

Rhogam

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Rh0 immunoglobulin, also called anti-Rh or anti-D immunoglobulin.

An injectable blood product used to protect an Rh-positive fetus from antibodies by its Rh-negative mother.

The idea underlying Rhogam is if anti-Rh antibody is given soon after delivery, it blocks the sensitization of the mother and prevents Rh disease from occurring in the woman's next Rh-positive child.

Rhogam is now given routinely to Rh-negative women after pregnancies in which they carried Rh-positive fetuses to prevent the mother's immune system from reacting to the Rh-positive blood of any subsequent fetus.

Rhogam was developed in the 1960s by Dr.

Vincent J.

Freda (1927-2003), professor of obstetrics and gynecology at Columbia University

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