Letter V

VEGF

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Vascular endothelial growth factor, a substance made by cells that stimulates the formation of new blood vessels, a process called angiogenesis.

VEGF also acts as a mitogen for vascular endothelial (vessel lining) cells, stimulating these cells to divide and multiply.</P> VEGF is a polypeptide.

It is structurally related to platelet-derived growth factor (PDGF).

The gene for VEGF is on chromosome 6p12.

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